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Delineation of two drug-responsive anxiety syndromes

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  1. Ask-Upmark, E.: Life and death without ovaries. Acta med. scand.172, 129–135 (1962).

    Google Scholar 

  2. Ayd, F. J.: Current status of the major antidepressants. Amer. psychiat. Ass. Psychiat. Res. Rep. 213–216 (1959).

  3. Bowlby, J.: Personality and mental illness. London: Kegan Paul, Trench, Trubner & Co. Ltd. 1940.

    Google Scholar 

  4. —: Separation anxiety. Int. J. Psycho-Anal.41, 89–113 (1960).

    Google Scholar 

  5. Clyde, D. J.: Manual for the Clyde Mood Scale. Biometric Laboratory University of Miami, Coral Gables, Fla. 1963.

    Google Scholar 

  6. Frank, J. D., L. H. Gliedman, S. D. Imber, A. R. Stone, andE. H. Nash: Patients' expectancies and relearning as factors determining improvement in psychotherapy. Amer. J. Psychiat.115, 961–968 (1959).

    Google Scholar 

  7. Freud, S.: On the grounds for detaching a particular syndrome from neurasthenia under the description ‘anxiety neurosis’. Stand. Ed.3, 90–115 (1895).

    Google Scholar 

  8. Goldman, D.: The effects of “energizers” on neurotic patients. Dis. nerv. Syst.23, 11, 1–8 (1962).

    Google Scholar 

  9. Klein, D. F., andM. Fink: Psychiatric reaction patterns to imipramine. Amer. J. Psychiat.119, 432–438 (1962a).

    Google Scholar 

  10. — —: Behavioral reaction patterns with phenothiazines. Arch. gen. Psychiat.7, 449–459 (1962b).

    Google Scholar 

  11. — —: Multiple item factors as change measures in psychopharmacology. Psychopharmacologia (Berl.)4, 43–52 (1963).

    Google Scholar 

  12. Lieberman, M. A., D. Stock, andR. M. Whitman: Self-perceptual patterns among ulcer patients. Arch. gen. Psychiat.1, 167–176 (1959).

    Google Scholar 

  13. Lorr, M., R. L.Jenkins, and J. Q.Holsopple: Multidimensional scale for rating psychiatric patients, hospital form. Veterans Adm. Tech. Bull. No. 10 (1953).

  14. —,J. P. O'Connor, andJ. W. Stafford: The psychotic reaction profile. J. clin. Psych.16, 241–245 (1960).

    Google Scholar 

  15. Roth, M.: The phobic anxiety-depersonalization syndrome and some general aetiological problems in psychiatry. J. Neuropsychiat.1, 293–306 (1960).

    Google Scholar 

  16. Sargant, W.: The treatment of anxiety states and atypical depressions by the monoamine oxidase inhibitor drugs. J. Neuropsychiat.3, Suppl. 1, 96–103 (1962).

    Google Scholar 

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Aided, in part, by grants MY-02715 and MY-04798 of the National Institute of Mental Health, United States Public Health Service. The cooperation of Geigy Pharmaceuticals and Smith, Kline and French Laboratories is gratefully acknowledged.

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Klein, D.F. Delineation of two drug-responsive anxiety syndromes. Psychopharmacologia 5, 397–408 (1964).

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  • Anxiety Syndrome