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High frequency oscillation

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Abstract

During high frequency oscillation (HFO) small volumes are delivered at frequencies up to 40 Hz; both inspiration and expiration are active. Oxygenation is controlled by the mean airway pressure level and carbon dioxide elimination by the delivered volume and, less so, by frequency. In some infants the delivered volume can be 50%–100% of the dead space. Measurements during HFO demonstrate oscillator performance can be impaired at high frequencies. HFO may be a useful alternative to extra corporeal membrane oxygenation in infants with severe respiratory failure, but its role in reducing bronchopulmonary dysplasia remains controversial.

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Abbreviations

AaDo2 :

arterial alveolar oxygen difference

BPD :

bronchopulmonary dysplasia

CMV :

conventional ventilation

ECMO :

extra corporeal membrane oxygenation

HFJV :

high frequency jet ventilation

HFO :

high frequency oscillation

IVH :

intraventricular haemorrhage

MAP :

mean airway pressure

RDS :

respiratory distress syndrome

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Authors and Affiliations

  1. Department of Child Health, King's College Hospital, SE5 9RS, London, UK

    Anne Greenough

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  1. Anne Greenough
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Greenough, A. High frequency oscillation. Eur J Pediatr 153 (Suppl 2), S2–S6 (1994). https://doi.org/10.1007/BF02179665

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  • DOI: https://doi.org/10.1007/BF02179665

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