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Agents and Actions

, Volume 13, Issue 5–6, pp 501–503 | Cite as

Activation of rabbit blood platelets by endotoxin: Significance of thromboxane biosynthesis and release reaction

  • Hidde Bult
  • Gert M. Laekeman
  • Arnold G. Herman
Microcirculatory Events

Keywords

Thromboxane Blood Platelet Release Reaction Rabbit Blood Thromboxane Biosynthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. [1]
    D.E. MacIntyre, A.P. Allen, K.J.I. Thorne, A.M. Glauert andJ.L. Gordon,Endotoxin-induced platelet aggregation and secretion. 1. Morphological changes and pharmacological effects, J. Cell Sci.28, 211–223 (1977).Google Scholar
  2. [2]
    N. Semeraro, Interactions of platelets leucocytes, and endothelium with bacterial endotoxins: possible relevance in kidney disorders. InHemostasis, Prostaglandins and Renal Disease, pp. 99–116. (Eds.G. Remuzzi, G. Mecca andG. de Gaetano). Raven Press, New York (1980).Google Scholar
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    I.F. Charo, R.D. Feinman andT.C. Detwiler,Interrelations of platelet aggregation and secretion, J. clin. Invest.60, 866–873 (1977).Google Scholar
  4. [4]
    H. Bult, J. Beetens andA.G. Herman,Blood levels of 6-oxo-prostaglandin F during endotoxin-induced hypotension in rabbits, Eur. J. Pharmac.63, 47–56 (1980).Google Scholar
  5. [5]
    E. Gränström andH. Kindahl, Radioimmunoassay of prostaglandins and thromboxanes. InAdvances in Prostaglandin and Thromboxane Research, vol. 5, pp. 176–179. (Ed.J.C. Frölich). Raven Press, New York 1978.Google Scholar
  6. [6]
    H. Bult andA.G. Herman,Thromboxane A 2 biosynthesis during endotoxin-induced aggregation of platelets from normal and sensitized guinea pigs, Agents and Actions9, 560–565 (1979).Google Scholar

Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • Hidde Bult
    • 1
  • Gert M. Laekeman
    • 1
  • Arnold G. Herman
    • 1
  1. 1.Department of Experimental PharmacologyUniversity of AntwerpWilrijkBelgium

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