Agents and Actions

, Volume 13, Issue 5–6, pp 501–503 | Cite as

Activation of rabbit blood platelets by endotoxin: Significance of thromboxane biosynthesis and release reaction

  • Hidde Bult
  • Gert M. Laekeman
  • Arnold G. Herman
Microcirculatory Events


Thromboxane Blood Platelet Release Reaction Rabbit Blood Thromboxane Biosynthesis 
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    D.E. MacIntyre, A.P. Allen, K.J.I. Thorne, A.M. Glauert andJ.L. Gordon,Endotoxin-induced platelet aggregation and secretion. 1. Morphological changes and pharmacological effects, J. Cell Sci.28, 211–223 (1977).Google Scholar
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    N. Semeraro, Interactions of platelets leucocytes, and endothelium with bacterial endotoxins: possible relevance in kidney disorders. InHemostasis, Prostaglandins and Renal Disease, pp. 99–116. (Eds.G. Remuzzi, G. Mecca andG. de Gaetano). Raven Press, New York (1980).Google Scholar
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    I.F. Charo, R.D. Feinman andT.C. Detwiler,Interrelations of platelet aggregation and secretion, J. clin. Invest.60, 866–873 (1977).Google Scholar
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    E. Gränström andH. Kindahl, Radioimmunoassay of prostaglandins and thromboxanes. InAdvances in Prostaglandin and Thromboxane Research, vol. 5, pp. 176–179. (Ed.J.C. Frölich). Raven Press, New York 1978.Google Scholar
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    H. Bult andA.G. Herman,Thromboxane A 2 biosynthesis during endotoxin-induced aggregation of platelets from normal and sensitized guinea pigs, Agents and Actions9, 560–565 (1979).Google Scholar

Copyright information

© Birkhäuser Verlag 1983

Authors and Affiliations

  • Hidde Bult
    • 1
  • Gert M. Laekeman
    • 1
  • Arnold G. Herman
    • 1
  1. 1.Department of Experimental PharmacologyUniversity of AntwerpWilrijkBelgium

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