Skip to main content
Log in

Abstract

Corneal keloids, elevated corneal scars that protrude beyond the original site of injury, were found in nine globes enucleated from young African patients with the diagnosis of anterior staphyloma. All the cases showed evidence of previous corneal perforation and protuberant hypertrophic scar of the anterior corneal stroma. Corneal keloids may be more common than previously thought, and may be related to over production of collagen in the scar tissue of susceptible individuals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Sauer GC (1973) Manual of Skin Diseases. Philadelphia, JB Lippincott Company, pp 272–275

    Google Scholar 

  2. Smith HC (1940) Keloid of the cornea. Trans Am Ophthalmol Soc 38: 519–538

    Google Scholar 

  3. Fenton RH, Tredici TJ (1964) Hypertrophic corneal scars (keloids). Surv Ophthalmol 6: 561–566

    Google Scholar 

  4. Farkas TG, Znajda JP (1968) Keloid of the cornea. Am J Ophthalmol 66: 319–323

    Google Scholar 

  5. Frederique G, Howard RO, Boniuk V (1969) Corneal ulcers in rubeola. Am J Ophthalmol 68: 996–1003

    Google Scholar 

  6. O'Grady RB, Kirk HQ (1972) Corneal keloids. Am J Ophthalmol 73: 206–213

    Google Scholar 

  7. Shukla IM, Arora NP, Arora MM (1975) Corneal keloid. Ind J Ophthalmol 23: 18–19

    Google Scholar 

  8. Lewis GM, Wheeler CE Jr (1967) Practical Dermatology 3rd ed. Philadelphia, WB Saunders Company, pp 525–527

    Google Scholar 

  9. Lever WF (1967) Histopathology of the skin. Philadelphia, JB Lippincott Company, pp 622–626

    Google Scholar 

  10. Clore JN, Cohen IK, Diegelmann RF (1979) Quantitative assay of types I and III collagen synthesized by keloid biopsies and fibro-blasts. Biochim Biophys Acta 586: 384–390

    Google Scholar 

  11. Cohen IK, Diegelmann RF, McCoy BJ (1977) Elevated collagen synthesis in cultured keloid fibroblasts. Surg Form 28: 526–527

    Google Scholar 

  12. Diegelmann RF, Cohen IK, McCoy BJ (1979) Growth kinetics and collagen synthesis of normal skin, normal scar and keloid fibroblasts in vitro. J Cell Physiol 98: 341–346

    Google Scholar 

  13. Conn HF (1975) Current Therapy 1975. Philadelphia, WB Saunders Company, pp 581–589

    Google Scholar 

  14. McCoy BJ, Diegelmann RF, Cohen IK (1980) In vitro inhibition of cell growth, collagen synthesis, and prolyl hydroxylase activity by triamcinolone acetonide (40750). Proc Soc Exp Biol Med 163: 216–222

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Dr. Cadet is a Fellow of the International Eye Foundation at the Cornea Service, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lahav, M., Cadet, J.C., Chirambo, M. et al. Corneal keloids — A histopathological study. Graefe's Arch Clin Exp Ophthalmol 218, 256–261 (1982). https://doi.org/10.1007/BF02175893

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02175893

Keywords

Navigation