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The comparative enhancement of the depressant action of alcohol by eight representative ataractic and analgesic drugs

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Zusammenfassung

Eine Methode zur Messung der Potenzierung von Tranquilizern und Analgetika auf Äthanoldepression wird beschrieben. Unbeweglichkeit von Mäusen wird als Kriterium der Depression genommen. Die fünf Tranquilizer, die gebraucht wurden, haben Äthanol in verschiedenen Graden potenziert. Von den drei analgetischen Drogen hat Morphin, nicht aberd-Propoxyphen und Codein, Äthanolnarkose potenziert.

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Authors and Affiliations

  1. Department of Pharmacology, Indiana University School of Medicine, Indianapolis, U.S.A.

    R. B. Forney, H. R. Hulpieu & F. W. Hughes

Authors
  1. R. B. Forney
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  2. H. R. Hulpieu
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  3. F. W. Hughes
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Additional information

This study was supported (in part) by a P.H.S. research grant AC-20 from the Division of Accident Prevention, Bureau of State Services, Public Health Service.

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Forney, R.B., Hulpieu, H.R. & Hughes, F.W. The comparative enhancement of the depressant action of alcohol by eight representative ataractic and analgesic drugs. Experientia 18, 468–470 (1962). https://doi.org/10.1007/BF02175865

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  • DOI: https://doi.org/10.1007/BF02175865

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