Summary
After intrathoracic inoculation of laboratory-bredAedes aegypti mosquitoes with 3 Yukon isolates of California encephalitis (CE) virus (snowshoe hare subtype), Northway (NOR) and Murray Valley encephalitis (MVE) viruses, viral replication was observed following incubation at 13, 21, 35 and 39° C, which constituted the full temperature range of viability ofA. aegypti. Rates of viral replication were reduced at low temperatures and accelerated at high temperatures. Virus-specific immunoperoxidase staining of mosquito salivary glands occurred regularly after thoraces attained maximum infectivity levels. At 13 and 21° C, mosquitoes were infected by 10 to 100 times less CE and MVE viruses than mice, but about 10 times more NOR virus was required to infect mosquitoes than mice.
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McLean, D.M., Grass, P.N., Miller, M.A. et al. Arbovirus growth inAedes aegypti mosquitoes throughout their viable temperature range. Archives of Virology 49, 49–57 (1975). https://doi.org/10.1007/BF02175595
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DOI: https://doi.org/10.1007/BF02175595