Analysis of intraocularly applied silicone oils of various origins

  • V. -P. Gabel
  • A. Kampik
  • J. Burkhardt
Original Investigations


Complications during the intraocular use of silicone oil can be caused by two factors: first, mechanical interaction with the surrounding tissue and, second, the physicochemical properties of the oil itself. The properties of 14 oils of various origins in clinical use were investigated: 12 of the 14 oils contained various amounts of low-molecular-weight components (cyclosiloxanes and molecules with a molecular weight of less than 2400), which are able to diffuse into the surrounding tissue and may incite toxic or inflammatory reactions. Some of the samples had a tenfold lower volume resistivity than others, an indicator of the presence of ionic impurities, such as catalyst remnants, which may also be responsible for adverse reactions.


Public Health Silicone Molecular Weight Physicochemical Property Lower Volume 
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Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • V. -P. Gabel
    • 1
  • A. Kampik
    • 1
  • J. Burkhardt
    • 2
  1. 1.Universitäts-AugenklinikMünchen 2Federal Republic of Germany
  2. 2.Abteilung N, Wacker-ChemieBurghausenFederal Republic of Germany

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