Summary
Ulcers of the stomac of guinea-pigs, produced by subcutaneous application of histamine, are reduced to a significant degree in number by peroral application of antihistaminics. The effect is corresponding to the given dosage. Pyribenzamin proved to be the most effective.
References
B. N. Halpern, C. R. Soc. Biol.140, 361, 363 und 830 (1946).
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Schuler, W. Über die Wirkung von Pyribenzamin und anderen Antihistaminika auf die durch Histaminverabreichung erzeugten Magenulzera. Experientia 5, 361–362 (1949). https://doi.org/10.1007/BF02174516
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DOI: https://doi.org/10.1007/BF02174516