Interaction of human immunodeficiency virus type 1 envelope protein with liposomes containing galactosylceramide

Summary

The glycosphingolipid galactosylceramide (GalCer) has been identified as an alternate receptor for the human immunodeficiency virus type 1 (HIV-1). Here we review a liposome flotation assay used to study the interaction of the HIV-1 envelope glycoprotein (env) with artificial membrane vesicles containing GalCer. The properties of binding, the nature of the env binding site for GalCer, and the implications of this interaction for HIV-1 infection are discussed.

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References

  1. 1

    Dalgleish, A.G., Beverley, P.C.L., Clapham, P.R., Crawford, D.H., Greaves, M.F. and Weiss, R.A., Nature, 312 (1984) 763.

    Google Scholar 

  2. 2

    Klatzmann, D., Champagne, E., Chamaret, S., Gruest, J., Guetard, D., Hercend, T., Gluckman, J.C. and Montagnier, L., Nature, 312 (1984) 767.

    Google Scholar 

  3. 3

    Popovic, M., Lange-Wantzin, G., Sarin, P.S., Mann, D. and Gallo, R.C., Proc. Natl. Acad. Sci. USA, 80 (1983) 5402.

    Google Scholar 

  4. 4

    Klatzmann, D., Barre-Sinoussi, F., Nugeyre, M.T., Dauguet, C., Vilmer, E., Griscelli, C., Brun-Vezinet, F., Rouzioux, C., Gluckman, J.C., Chermann, J.-C. and Montagnier, L., Science, 225 (1984) 59.

    Google Scholar 

  5. 5

    Chen, I.S.Y., Quan, S.G. and Golde, D.W., Proc. Natl. Acad. Sci. USA, 80 (1983) 7006.

    Google Scholar 

  6. 6

    Ho, D.D., Rota, T.R. and Hirsch, M.S., J. Clin. Invest., 77 (1986) 1712.

    Google Scholar 

  7. 7

    Levy, J.A., Shimabukuro, J., McHugh, T., Casavant, C., Stites, D. and Oshiro, L., Virology, 147 (1985) 441.

    Google Scholar 

  8. 8

    Von Briesen, H., Andreesen, R. and Rubsamen-Waigmann, H., Virology, 178 (1990) 597.

    Google Scholar 

  9. 9

    Schwartz, S., Felber, B.K., Fenyo, E.-M. and Pavlakis, G.N., Proc. Natl. Acad. Sci. USA, 86 (1989) 7200.

    Google Scholar 

  10. 10

    Cann, A.J., Zack, J.A., Go, A.S., Arrigo, S.J., Koyanagi, Y., Green, Y., Green, P.L., Koyanagi, Y., Pang, S. and Chen, I.S.Y., J. Virol., 64 (1990) 4735.

    Google Scholar 

  11. 11

    O'Brien, W.A., Koyanagi, Y., Namazi, A., Zhao, J.-Q., Diagne, A., Idler, K., Zack, J.A. and Chen, I.S.Y., Nature, 348 (1990) 69.

    Google Scholar 

  12. 12

    York-Higgins, D., Cheng-Mayer, C., Bauer, D., Levy, J.A. and Dina, D., J. Virol., 64 (1990) 4016.

    Google Scholar 

  13. 13

    Huang, Z.B., Potash, M.J., Simm, M., Shahabuddin, M., Chao, W., Gendelman, H.E., Eden, E. and Volsky, D.J., J. Virol., 67 (1993) 6893.

    Google Scholar 

  14. 14

    Schmidtmayerova, H., Bolmont, C., Baghdiguian, S., Hirsch, I. and Chermann, J.C., Virology, 190 (1992) 124.

    Google Scholar 

  15. 15

    Maddon, P.J., Dalgleish, A.G., McDougal, J.S., Clapham, P.R., Weiss, R.A. and Axel, R., Cell, 47 (1986) 333.

    Google Scholar 

  16. 16

    Clapham, P.R., Blanc, D. and Weiss, R.A., Virology, 181 (1991) 703.

    Google Scholar 

  17. 17

    Ashorn, P.A., Berger, E.A. and Moss, B., J. Virol., 64 (1990) 2149.

    Google Scholar 

  18. 18

    Dragic, T., Charneau, P., Clavel, F. and Alizon, M., J. Virol., 66 (1992) 4794.

    Google Scholar 

  19. 19

    Broder, C.C., Dimitrov, D.S., Blumenthal, R. and Berger, E.A., Virology, 193 (1993) 483.

    Google Scholar 

  20. 20

    Dragic, T., Picard, L. and Alizon, M., J. Virol., 69 (1995) 1013.

    Google Scholar 

  21. 21

    Levy, J.A., HIV and the Pathogenesis of AIDS, American Society for Microbiology, Washington, DC, 1994.

    Google Scholar 

  22. 22

    Harouse, J.H., Bhat, S., Spitalnik, S.L., Laughlin, M., Stefano, K., Silberberg, D.H. and Gonzalez-Scarano, F., Science, 253 (1991) 320.

    Google Scholar 

  23. 23

    Yahi, N., Baghdiguian, S., Moreau, H. and Fantini, J., J. Virol., 66 (1992) 4848.

    Google Scholar 

  24. 24

    Long, D., Berson, J.F., Cook, D.G. and Doms, R.W., J. Virol., 68 (1994) 5890.

    Google Scholar 

  25. 25

    Earl, P.L., Moss, B. and Doms, R.W., J. Virol., 65 (1991) 2047.

    Google Scholar 

  26. 26

    Earl, P.L., Doms, R.W. and Moss, B., Proc. Natl. Acad. Sci. USA, 87 (1990) 648.

    Google Scholar 

  27. 27

    Pinter, A., Honnen, W.J., Tilley, S.A., Bona, C., Zaghouani, H., Gorny, M.K. and Zolla-Pazner, S., J. Virol., 63 (1989) 2674.

    Google Scholar 

  28. 28

    Schawaller, M., Smith, C.E., Skehel, J.J. and Wiley, D.C., Virology, 172 (1989) 367.

    Google Scholar 

  29. 29

    McKeating, J.A. and Willey, R.L., Aids, 3 (1989) S35.

  30. 30

    McCune, J.M., Rabin, L.B., Feinberg, M.B., Lieberman, M., Kosek, J.C., Reyes, G.R. and Weissman, I.L., Cell, 53 (1988) 55.

    Google Scholar 

  31. 31

    Willey, R.L., Bonifacino, J.S., Potts, B.J., Martin, M.A. and Klausner, R.D., Proc. Natl. Acad. Sci. USA, 85 (1988) 9580.

    Google Scholar 

  32. 32

    Bosch, M.L., Earl, P.L., Fargnoli, K., Picciafuoco, S., Giombini, F., Wong-Stahl, F. and Franchini, G., Science, 244 (1989) 694.

    Google Scholar 

  33. 33

    Kowalski, M., Potz, J., Basiripour, L., Dorfman, T., Goh, W.C., Terwillger, E., Dayton, A., Rosen, C., Haseltine, W. and Sodroski, J., Science, 237 (1987) 1351.

    Google Scholar 

  34. 34

    White, J.M., Science, 258 (1992) 917.

    Google Scholar 

  35. 35

    McClure, M.O., Marsh, M. and Weiss, R.A., EMBO J., 7 (1988) 513.

    Google Scholar 

  36. 36

    Stein, B.S., Gowda, S.D., Lifson, J.D., Penhallow, R.C., Bensch, K.G. and Engelman, E.G., Cell, 49 (1987) 659.

    Google Scholar 

  37. 37

    Fantini, J., Cook, D.G., Nathanson, N., Spitalnik, S.L. and Gonzalez-Scarano, F., Proc. Natl. Acad. Sci. USA, 90 (1993) 2700.

    Google Scholar 

  38. 38

    Bhat, S., Spitalnik, S.L., Gonzalez-Scarano, F. and Silberberg, D.H., Proc. Natl. Acad. Sci. USA, 88 (1991) 7131.

    Google Scholar 

  39. 39

    Furuta, Y., Eriksson, K., Svennerholm, B., Fredman, P., Horal, P., Jeansson, S., Vahlne, A., Holmgren, J. and Czerkinsky, C., Proc. Natl. Acad. Sci. USA, 91 (1994) 12559.

    Google Scholar 

  40. 40

    Baccetti, B., Benedetto, A., Burrini, A., Collodel, G., Ceccarini, E.C., Crisa, N., DiCaro, A., Estenoz, M., Garbuglia, A.R., Massacesi, A., Piomboni, P., Renieri, T. and Solazzo, D., J. Cell Biol., 127 (1994) 903.

    Google Scholar 

  41. 41

    Brown, D.A., Trends Cell Biol., 2 (1992) 338.

    Google Scholar 

  42. 42

    Merrill A.H. Jr., Hannun, Y.A. and Bell, R.M., Adv. Lipid Res., 25 (1993) 1.

    Google Scholar 

  43. 43

    Monco, J.C.G., Villar, B.F., Rogers, R.C., Szczepanski, A., Wheeler, C.M. and Benach, J.L., Neurology, 42 (1992) 1341.

    Google Scholar 

  44. 44

    Karlsson, K.-A., Annu. Rev. Biochem., 58 (1989) 309.

    Google Scholar 

  45. 45

    Superti, F. and Donelli, G., J. Gen. Virol., 72 (1991) 2467.

    Google Scholar 

  46. 46

    Willoughby, R.E., Yolken, R.H. and Schnarr, R.L., J. Virol., 64 (1990) 4830.

    Google Scholar 

  47. 47

    Van Meer, G., Curr. Opin. Cell Biol., 5 (1993) 661.

    Google Scholar 

  48. 48

    Van Meer, G., Annu. Rev. Cell Biol., 5 (1989) 247.

    Google Scholar 

  49. 49

    Ruocco, M.J., and Shipley, G.G., Biophys. J., 43 (1983) 91.

    Google Scholar 

  50. 50

    Thompson, T.E. and Tillack, T.W., Annu. Rev. Biophys. Chem., 14 (1985) 387.

    Google Scholar 

  51. 51

    Brown, D.A. and Rose, J.K., Cell, 68 (1992) 533.

    Google Scholar 

  52. 52

    Fiedler, K., Kobayashi, T., Kurzchalia, T.V. and Simons, K., Biochemistry, 32 (1993) 6365.

    Google Scholar 

  53. 53

    Pascher, I. and Sundell, S., Chem. Phys. Lipids, 20 (1977) 175.

    Google Scholar 

  54. 54

    Stromberg, N., Nyholm, P.-G., Pascher, I. and Normark, S., Proc. Natl. Acad. Sci. USA, 88 (1991) 9340.

    Google Scholar 

  55. 55

    Earl, P. and Moss, B., In Ausubel, F.M., Brent, R., Kingston, R.E., Moore, D.D., Seidman, J.G., Smith, J.A. and Struhl, K. (Eds.) Current Protocols in Molecular Biology, Wiley-Interscience, New York, NY, 1991, pp. 16151–16155.

    Google Scholar 

  56. 56

    Cullen, B.R., Infect. Agents Dis., 3 (1994) 68.

    Google Scholar 

  57. 57

    Linsley, P.S., Ledbetter, J.A., Kinney-Thomas, E. and Hu, S.-L., J. Virol., 62 (1988) 3695.

    Google Scholar 

  58. 58

    Szoka F. Jr., Papahadjopoulos, D., Proc. Natl. Acad. Sci. USA, 75 (1978) 4194.

    Google Scholar 

  59. 59

    Cook, D.G., Fantini, J., Spitalnik, S.L. and Gonzalez-Scarano, F., Virology, 201 (1994) 206.

    Google Scholar 

  60. 60

    Sixma, T.K., Pronk, S.E., Kalk, K.H., Van Zanten, B.A.M., Berghuis, A.M. and Hol, W.G.J., Nature 355 (1992) 561.

    Google Scholar 

  61. 61

    Holgersson, J., Jovall, P.-A. and Breimer, M.E., J. Biochem., 110 (1991) 120.

    Google Scholar 

  62. 62

    Suzuki, K., In Siegel, G.J., Albers, R.W., Agranoff, B.W. and Katzman, R. (Eds.) Basic Neurochemistry, Little, Brown and Co., Boston, MA, 1981, pp. 355–370.

    Google Scholar 

  63. 63

    Bansal, R., Warrington, A.E., Gard, A.L., Ranscht, B. and Pfeiffer, S.E., J. Neurosci. Res., 24 (1989) 548.

    Google Scholar 

  64. 64

    Yahi, N., Sabatier, J.-M., Baghdiguian, S., Gonzalez-Scarano, F. and Fantini, J., J. Virol., 69 (1995) 320.

    Google Scholar 

  65. 65

    Bhat, S., Mettus, R.V., Reddy, E.P., Ugen, K.E., Srikanthan, V., Williams, W.V. and Weiner, D.B., Aids Res. Hum. Retroviruses, 9 (1993) 175.

    Google Scholar 

  66. 66

    Moore, J.P. and Nara, P.L., Aids, 5 (1991) S21.

  67. 67

    Doms, R.W., Helenius, A. and White, J., J. Biol. Chem., 260 (1985) 2973.

    Google Scholar 

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Correspondence to Robert W. Doms.

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Berson, J.F., Doms, R.W. & Long, D. Interaction of human immunodeficiency virus type 1 envelope protein with liposomes containing galactosylceramide. Perspectives in Drug Discovery and Design 5, 169–180 (1996). https://doi.org/10.1007/BF02174012

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Keywords

  • Polymer
  • Human Immunodeficiency Virus
  • Binding Site
  • Virus Type
  • Membrane Vesicle