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L'influence des hormones cortico-surrénaliennes sur la régénération de l'épithélium cornéen du lapin; les problèmes statistiques que posent ces expériences

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Summary

After performing an abrasion of the rabbit's cornea (5 mm), the authors studied the action of a suspension in physiological serum of desoxycorticosterone 1 and 5% and Cortisone 2.5% on the epithelial regeneration of the cornea. The “test cornea” received physiological serum.

The experiments were laid out in a so-called “balanced incomplete bloc design”. With such a planning of the experiments, there is an increase in precision which is estimated to be of 560%. Epithelisation times are:

  • 51.2 hours for the test cornea which received physiological serum;

  • 53.6 for desoxycorticosterone 5%;

  • 55.8 for desoxycorticosterone 1%;

  • 58.6 for Cortisone 2.5%.

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Authors and Affiliations

  1. Laboratoire de la clinique ophtalmologique et Laboratoire de statistique mathématique de l'Université de Genève, Switzerland

    J. B. Bourquin & A. Linder

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  1. J. B. Bourquin
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  2. A. Linder
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Bourquin, J.B., Linder, A. L'influence des hormones cortico-surrénaliennes sur la régénération de l'épithélium cornéen du lapin; les problèmes statistiques que posent ces expériences. Experientia 8, 194–196 (1952). https://doi.org/10.1007/BF02173742

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  • DOI: https://doi.org/10.1007/BF02173742

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