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Recurrent multiple-branch retinal arteriolar occlusions in a patient with protein C deficiency

  • Michael E. Nelson
  • John F. Talbot
  • F. Eric Preston
Clinical Investigations

Abstract

A 34-year-old woman is presented who has recurrent, multiple, retinal arteriolar occlusions associated with a deficiency in protein C, a vitamin K-dependent anticoagulant. Protein C is a naturally occurring anticoagulant and if there is a deficiency, it can lead to episodes of thrombosis; the deficiency can be acquired or congenital. This is the first documented case of retinal arteriolar occlusion associated with a congenital deficiency of this protein. The mechanism for arteriolar occlusion in this patient is discussed, and whilst the role of protein C deficiency remains presumptive, it is strongly implicated.

Keywords

Public Health Documented Case Retinal Arteriolar Congenital Deficiency Arteriolar Occlusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag, Berlin Heidelberg 1989

Authors and Affiliations

  • Michael E. Nelson
    • 1
  • John F. Talbot
    • 1
  • F. Eric Preston
    • 2
  1. 1.Department of OphthalmologyRoyal Hallamshire HospitalSheffieldUK
  2. 2.Department of HaematologyRoyal Hallamshire HospitalSheffieldUK

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