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Human cornea: Individual responses to hypoxic environments

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Abstract

Using a micropolarographic system, the responses of seven human corneas to oxygen atmospheres ranging from 20.9% to 0% were measured. Under normal atmospheric conditions, ratios of oxygen demand were observed between corneas as great as 1.23:1. Following 0% oxygen conditions, however, these ratios rose to a maximum of 1.93:1, i.e., representing demand differences between particular corneas of nearly 2:1. Such differences may prove increasingly important in the gauging of patient suitability and safety in relation to hypoxic stress, e.g., the extended wear of contact lenses.

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Benjamin, W.J., Hill, R.M. Human cornea: Individual responses to hypoxic environments. Graefe's Arch Clin Exp Ophthalmol 226, 45–48 (1988). https://doi.org/10.1007/BF02172717

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  • DOI: https://doi.org/10.1007/BF02172717

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