Summary
In view of the chronic interstitial nephritis observed in man after years of abuse of phenacetin-containing analgesics, rats were subjected to oral loading-tests with Saridon and its active components. It was not possible, however, to induce interstitial nephritis experimentally. Trials with Saridon will be continued on rats having undergone additional renal loading-tests and in which renal damage has been previously induced.
References
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Kristallographisch identifiziert durchH. Waldmann.
Mikroanalytische Bestimmungen durchJ. Würsch.
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Studer, A., Zbinden, G. Experimenteller Beitrag zur Frage von Nierenschäden bei Abusus von phenazetinhaltigen Schmerzmitteln. Experientia 11, 450–451 (1955). https://doi.org/10.1007/BF02172556
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DOI: https://doi.org/10.1007/BF02172556