Summary
The biochemical effects on bone marrow of a same dose of X rays (700 r) induced by a total body irradiation or a local irradiation are compared. The ribonucleic acid and the desoxyribonucleic acid of bone marrow show a fall during days 2 to 14 after irradiation, followed by complete recovery on day 21. A significant difference is noted during this period between animals exposed to a total or local irradiation system. The changes consecutive to X rays induced by a total irradiation are prominenter and remain longer than in local irradiation. The direct effect of X rays is probably associated with secondary injury of physiological connexions or other substances affected in total body irradiation.
References
P. Mandel etJ. Rodesch, J. Physiol.47, 234 (1955).
J. Rodesch etP. Mandel, C. r. Soc. Biol. (1955), sous presse.
P. Mandel etJ. Rodesch, Symposium de Radiobiologie (Liège 1954).
P. Mandel, P. Metais, Ch. M. Gros etR. Voegtlin, C. r. Acad. Sci.233, 1685 (1951).
G. Schmidt etS. J. Thannhauser, J. biol. Chem.161, 83 (1945).
W. Mejbaum, Z. physiol. Chem.258, 117 (1939).
A. P. Briggs, J. biol. Chem.53, 13 (1922).
Z. Dische, Microchem.2, 4 (1930).
Author information
Authors and Affiliations
Additional information
Travail effectué avec le concours matériel de l'Institut National d'Hygiène.
Rights and permissions
About this article
Cite this article
Rodesch, J., Jaudel, C., Chirpaz, B. et al. Action d'une dose unique de rayons X, administrée en irradiation totale ou locale, sur les acides nucléiques de la moelle osseuse chez le rat blanc. Experientia 11, 437–438 (1955). https://doi.org/10.1007/BF02172545
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02172545