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Preparation of tritiated vincaleukoblastine by the Wilzbach technique

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Zusammenfassung

Das Alkaloid Vincaleukoblastine (VLB) wurde als Base bei Anwendung der Wilzbach-Technik titriert. Die Verbindung, bis zur konstanten Aktivität gereinigt, enthielt kein Dihydro-VLB mehr. Das Alkaloid, als Sulfatsalz dem Tritium unterworfen, inkorporiert die Substanz nur geringfügig, wobei das Tritium enhaltende Dihydro-VLB ensteht.

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Literatur

  1. G. H. Svoboda, I. S. Johnson, M. Gorman, andN. Neuss, J. Amer. pharm. Assoc.51, 707 (1962).

    CAS  Google Scholar 

  2. K. E. Wilzbach, J. Amer. chem. Soc.79, 1013 (1962).

    Article  Google Scholar 

  3. M. L. Whisman andB. H. Eccleston, Nucleonics20, 98 (1962).

    CAS  Google Scholar 

  4. S. Rothchild (Editor),Advances in Tracer Methodology, vol. 1 (Plenum Press, New York 1963), p. 4.

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  5. N. Neuss, M. Gorman, H. E. Boaz, andN. J. Conf, J. Amer. chem. Soc.84, 1509 (1962).

    Article  CAS  Google Scholar 

  6. M. Gorman, N. Neuss, andK. Biemann, J. Amer. chem. Soc.24, 1058 (1962).

    Article  Google Scholar 

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Authors and Affiliations

  1. Lilly Research Laboratories, Indianapolis, Indiana, USA

    R. E. McMahon

Authors
  1. R. E. McMahon
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Supplied as VELBAN (vinblastine SO4-Lilly).

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McMahon, R.E. Preparation of tritiated vincaleukoblastine by the Wilzbach technique. Experientia 19, 434–435 (1963). https://doi.org/10.1007/BF02171535

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  • DOI: https://doi.org/10.1007/BF02171535

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