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Isolation of coenzyme B12 from liver of germ-free mice

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Zusammenfassung

Die enzymatische Synthese von Cobamid-Coenzymen ist aus Extrakten, die von Mikroorganismen gewonnen wurden, gut bekannt, nicht aber von Säugetiergeweben. Unsere Befunde mit Cobamid-Coenzymen in der Leber von keimfreien Mäusen scheint anzuzeigen, dass die Verwandlung von Vitamin B12 in Coenzymform von Enzymen der Säugetiergewebe katalysiert werden kann.

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Authors and Affiliations

  1. Laboratory of Neurochemistry, National Institute of Neurological Diseases and Blindness, and Laboratory of Germfree Animal Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

    R. O. Brady & W. L. Newton

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  1. R. O. Brady
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  2. W. L. Newton
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Brady, R.O., Newton, W.L. Isolation of coenzyme B12 from liver of germ-free mice. Experientia 19, 398–399 (1963). https://doi.org/10.1007/BF02171506

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