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Quantitative evidence for the two-gradient hypothesis in the primary induction

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Zusammenfassung

Die Einwirkung quantitativer Unterschiede induzierender Agenzien wurde untersucht. HeLa-Zellen, mit und ohne Wärmebehandlung, wurden in zwei verschiedenen Proportionen (4:1 bzw. 1:4) gemischt und als Induktor in Epidermisexplantaten des Molchkeimes benutzt. Das Resultat (Fig.) zeigt, dass der Induktor, der mehr Zellen ohne Wärmebehandlung enthält, mehr mesodermale, aber auch mehr deuterencephale Gebilde induziert. Das Resultat wird mit der Zwei-Gradienten-Hypothese der induzierenden Agenzien erklärt.

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References

  1. F. E. Lehmann, Rev. Suisse Zool.57, Suppl. 141 (1950).

    Google Scholar 

  2. T. Yamada, Embryologia1, 1 (1950).

    Article  Google Scholar 

  3. S. Toivonen andL. Saxén, Ann. Acad. Sci. Fenn. A. IV30, 1 (1955).

    Google Scholar 

  4. T. Yamada andK. Takata, J. exp. Zool.128, 291 (1955).

    Article  Google Scholar 

  5. L. Saxén andS. Toivonen, J. Embryol. exp. Morphol.6, 616 (1958).

    Google Scholar 

  6. S. Toivonen, J. Embryol. exp. Morphol.2, 239 (1954).

    Google Scholar 

  7. J. Holtfreter, Arch. exp. Zellforsch.15, 281 (1934).

    Google Scholar 

  8. H.-H. Chuang, Roux' Arch.139, 556 (1939).

    Article  Google Scholar 

  9. A. Dalcq, inFundamental Aspects of Normal and Malignant Growth (W. W. Nowinski, Ed., Elsevier Publ. Co., New York 1960), p. 305.

    Google Scholar 

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Authors and Affiliations

  1. Department of physiological Zoology, University of Helsinki, Finland

    S. Toivonen, L. Saxén & T. Vainio

Authors
  1. S. Toivonen
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  2. L. Saxén
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  3. T. Vainio
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Additional information

The investigation was supported by research grants from the Finnish State and the Sigrid Juselius Fund.

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Toivonen, S., Saxén, L. & Vainio, T. Quantitative evidence for the two-gradient hypothesis in the primary induction. Experientia 17, 86–87 (1961). https://doi.org/10.1007/BF02171440

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