, Volume 5, Issue 3, pp 201–203 | Cite as

Chinese medicine, Coix seeds increase peripheral cytotoxic T and NK cells

  • Yoh Hidaka
  • Tatsunari Kaneda
  • Nobuyuki Amino
  • Kiyoshi Miyai


Coix seeds, a Chinese medicine have been used in Japan and reported to be effective in patients with verruca vulgaris and verrucae planae juveniles. We investigated thein vivo effects on lymphocyte subsets in seven healthy volunteers who took six tablets of Coix seeds three times a day (a typical dose) for four weeks. Leukocyte counts and the percentage of total lymphocytes did not change but the percentages of CD3CD56+ cells and CD16+CD57 cells increased significantly. These results indicate that Coix seeds increase peripheral cytotoxic lymphocytes and may be effective to viral infection through the enhancement of cytotoxic activity.

Key words

Chinese medicine Coix seeds cytotoxic T cell natural killer cell 


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Copyright information

© Kluwer Academic Publishers 1992

Authors and Affiliations

  • Yoh Hidaka
    • 1
  • Tatsunari Kaneda
    • 1
  • Nobuyuki Amino
    • 1
  • Kiyoshi Miyai
    • 1
  1. 1.Department of Laboratory MedicineOsaka University Medical SchoolOsakaJapan

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