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Steatosi parenchimali da colchicina

Differenza di sensibilità dei due sessi in animali intossicati

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Summary

Some toxic effects of colchicine in mice were investigated.

The DL50 of the drug is reported to produce a fatty degeneration of the liver; the same takes place, to a lower degree, in the heart muscle and kidney parenchyma.

A better survival rate of the female than male mice treated with the same doses of colchicine was observed, the ratio being 1:4.

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Authors and Affiliations

  1. Laboratorio de Farmacología, Facultad de Medicina, Barcellona

    Silvano Rossi

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  1. Silvano Rossi
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Rossi, S. Steatosi parenchimali da colchicina. Experientia 6, 306–307 (1950). https://doi.org/10.1007/BF02170910

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  • DOI: https://doi.org/10.1007/BF02170910

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