Skip to main content
SpringerLink
Log in

Trace element analysis of placentas of alcoholics and controls with external beam PIXE

  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

External beam PIXE analysis with a protonbeam of 2.4 MeV was used to study trace element concentrations in human placentas. The aim was to check the suitability of PIXE analysis regarding soft tissue samples. Sample preparation was kept as simple as possible to avoid contamination or losses due to volatilization. The element of interest /Fe, Cu, Zn, Se, Br, Rb, and Sr/ were easily detected. A comparison was made with placental samples of alcoholics and abstinent controls to determine whether trace element concentrations in the placenta play a role in the pathogenesis of fetal alcohol syndrome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. P. Lemoine, H. Haronsseau, J.-P. Borteryu, J. C. Menuet,Quest Med. 25 /1968/ 476.

    Google Scholar 

  2. K. L. Jones, D. W. Smith, C. N. Ullelad A. P. Streissguth,Lancet I, /1973/ 1267.

  3. C. L. Randall, in: Pharmacological Treatment for Alcoholism /I. E. Griffith, J. M. Littleton, eds/ Croom Helm, Sidney, 1984, pp. 363–371.

    Google Scholar 

  4. C. J. McClain, L.-C. Su,Alcoholism: Clin. Exp. Res., 3 /1983/ 5.

    Google Scholar 

  5. M. J. Välimäki, K. J. Harju, R. H. Ylikahri,Clin. Chim. Acta, 130 /1983/ 291.

    PubMed  Google Scholar 

  6. M. H. Soltan, D. M. Jenkins,Br. J. Obst. Gyn., 89 /1982/ 56.

    Google Scholar 

  7. F. K. Ghishan, H. L. Greene,Pediatr. Res., 17 /1983/ 529.

    PubMed  Google Scholar 

  8. E. Halmesmäki, O. Ylikorkala, G. Alfthan,Br. Med. J., 291 /1985/ 1471.

    Google Scholar 

  9. T. B. Johansson, R. Akselsson, S. A. E. Johansson,Nucl. Instr. and Meth., 84 /1970/ 141.

    Google Scholar 

  10. G. S. Hall, N. Roach, M. Naumann, U. Simmons, H. Cong,Nucl. Instr. and Meth., B3 /1984/ 332.

    Google Scholar 

  11. S. A. E. Johansson,Nucl. Instr. and Meth., B3 /1984/ 1.

    Google Scholar 

  12. A. Anttila, J. Räisänsen, R. Lappalainen,Nucl. Instr. and Meth., B12 /1985/ 245.

    Google Scholar 

  13. J. Räisänen, A. Anttila,Nucl. Instr. and Meth., 196 /1982/ 489.

    Google Scholar 

  14. M. Hyvönen-Dabek, P. Nikkinen-Vilkki, J. T. Debek,Clin. Chem., 30 /1984/ 529.

    PubMed  Google Scholar 

  15. J. A. Cookson, J. L. Campbell,Nucl. Instr. and Meth., 216 /1983/ 489.

    Google Scholar 

  16. S. K. Biswas, M. Khaliquzzaman M. M. Islam, A. H. Khan,Nucl. Instr. and Meth., B3 /1984/ 337.

    Google Scholar 

  17. E. B. Dawson, M. P. Menon, R. E. Wainerdi, W. J. McGanity,J. Nucl. Med., 9 /1967/ 160.

    Google Scholar 

  18. R. J. Baglan, A. B. Brill, A. Schulert, D. Wilson, K. Larsen, N. Dyer, M. Mansour, W. Schaffner, L. Hoffman, J. Davies,Environ. Res., 8 /1974/ 64.

    PubMed  Google Scholar 

  19. R. Thieme, P. Schramel, B.-J. Klose, E. Waidl,Geburtsh. u. Frauenheilk., 35 /1975/ 349.

    Google Scholar 

  20. R. Thieme, P. Schramel, B.-J. Klose, E. Waidl,Geburtsh. u. Frauenheilk., 34 /1974/ 36.

    Google Scholar 

  21. G. V. Iyengar, W. E. Kollmer, H. J. M. Bowen, The Elemental Composition of Human Tissues and Body Fluids, Verlag Chemie, Weinheim, 1978.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physics, University of Helsinki, Siltavuorenpenger 20 D, 00170, Helsinki, Finland

    R. Lapatto

Authors
  1. R. Lapatto
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lapatto, R. Trace element analysis of placentas of alcoholics and controls with external beam PIXE. Journal of Radioanalytical and Nuclear Chemistry Letters 118, 349–359 (1987). https://doi.org/10.1007/BF02170468

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02170468

Keywords

Search

Navigation