Ciliary body neurilemoma recurring after 15 years

  • Thierry J. Hufnagel
  • Marvin L. Sears
  • Marc Shapiro
  • Jung H. Kim
Original Investigations

Abstract

A 57-year-old white female presented with a recurring neurilemoma (benign solitary schwannoma) of the ciliary body 15 years after the primary modified iridocyclectomy. As neurilemoma are encapsulated, successful “tumorectomy” was twice accomplished with total anatomical and functional preservation of the globe. The pathological diagnosis of spindle cell tumors of the uvea is discussed.

Keywords

Public Health Cell Tumor Spindle Cell Pathological Diagnosis Ciliary Body 

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References

  1. 1.
    Brewitt H, Huerkamp B, Richter K (1976) Ein Neurinom der Aderhaut. Klin Monatsbl Augenheilkd 169: 750–754Google Scholar
  2. 2.
    Callender GR, Thigpen CA (1930) Two neurofibromas in one eye. Am J Ophthalmol 13: 121–124Google Scholar
  3. 3.
    Donovan BF (1956) Neurilemoma of the ciliary body. Arch Ophthalmol 55: 672–675Google Scholar
  4. 4.
    Erlandson RA, Woodruff JM (1982) Peripheral nerve sheath tumors: an electron microscopic study of 43 cases. Cancer 49: 273–287Google Scholar
  5. 5.
    Ferry AP (1964) Lesions mistaken for malignant melanoma of the posterior uvea. Arch Ophthalmol 72: 463–469Google Scholar
  6. 6.
    François J (1947) Schwannome intraoculaire. Ann Oculist 180: 542–546Google Scholar
  7. 7.
    Freeman D (1934) Neurofibroma of the choroid. Arch Ophthalmol 11: 641–645Google Scholar
  8. 8.
    Gown AM, Vogel AM, Hoak D, Gough F, McNutt MA (1986) Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes. Am J Pathol 123: 195–203Google Scholar
  9. 9.
    Guillaumat ML, Loisillier MF (1952) Un cas de tumeur choroidienne àstructure histologique de neurinome. Bull Soc Ophthalmol Fr 52: 214–218Google Scholar
  10. 10.
    Harada M, Tamai M, Takei Y (1977) A case of intraocular neurilemoma. Folia Ophthalmol Jpn 28: 773–778Google Scholar
  11. 11.
    Harkin JC, Reed RJ (1969) Tumors of the peripheral nervous system. In: Firminger HL (ed) Atlas of tumor pathology, second series, Fasc 3. Armed Forces Institute of Pathology, Washington, DC, pp 93–94Google Scholar
  12. 12.
    Jakobiec FA, Witschel H, Zimmerman LE (1976) Choroidal leiomyoma of vascular origin. Am J Ophthalmol 82: 205–212Google Scholar
  13. 13.
    Jakobiec FA, Font RL, Tso MOM, Zimmerman LE (1977) Mesectodermal leiomyoma of the ciliary body. Cancer 39: 2102–2113Google Scholar
  14. 14.
    Maffee MF, Peyman GA, Grisolano JE, Fletcher ME, Spigos DG, Wehrli FM, Rasouli F, Capek V (1986) Malignant uveal melanoma and simulating lesions: MR imaging evaluation. Radiology 160: 773–780Google Scholar
  15. 15.
    Meyer SL, Fine BS, Font RL, Zimmerman LE (1968) Leiomyoma of the ciliary body. Electron microscopic verification. Am J Ophthalmol 66: 1061–1068Google Scholar
  16. 16.
    Moorhouse JH (1939) Case of neurofibroma of the choroid of acoustic nerve type. Trans Ophthalmol Soc UK 39: 416–420Google Scholar
  17. 17.
    Packard RBS, Harry J (1981) Choroidal neurilemmoma: an unusual clinical misdiagnosis. Br J Ophthalmol 65: 189–191Google Scholar
  18. 18.
    Papolczy F von (1932) Über ein aus einem hinteren Ciliarnerven entspringendes intraretrobulbäres Neurinom. Graefe's Arch Clin Exp Ophthalmol 128: 325–335Google Scholar
  19. 19.
    Reed RJ, Harkin JC (1983) Tumors of the peripheral nervous system. In: Hartmann WH (ed) Atlas of tumor pathology, second series, Fasc 3 (Suppl). Armed Forces Institute of Pathology, Washington, DC, p 22Google Scholar
  20. 20.
    Rosso R, Colombo R, Ricevuti G (1983) Neurilemmoma of the ciliary body: report of a case. Br J Ophthalmol 67: 585–587Google Scholar
  21. 21.
    Shields JA, Zimmerman LE (1973) Lesions simulating malignant melanoma of the posterior uvea. Arch Ophthalmol 89: 466–471Google Scholar
  22. 22.
    Shields JA, Augsburger JJ, Brown GC, Stephens RF (1980) The differential diagnosis of posterior uveal melanoma. Ophthalmology 87: 518–522Google Scholar
  23. 23.
    Shields JA, Sanborn GE, Kurz GH, Augsburger JJ (1981) Benign peripheral nerve tumor of the choroid. Report of a case and review of the literature. Ophthalmology 88: 1322–1329Google Scholar
  24. 24.
    Smith PA, Damato BE, Ko MK, Lyness RW (1987) Anterior uveal neurilemmoma: a rare neoplasm simulating malignant melanoma. Br J Ophthalmol 71: 34–40Google Scholar
  25. 25.
    Stough JT (1937) Intraocular neurofibroma. Report of a case. Arch Ophthalmol 18: 540–546Google Scholar
  26. 26.
    Stout AP (1935) The peripheral manifestations of the specific nerve sheath tumors (neurilemoma). Am J Cancer 24: 751–796Google Scholar
  27. 27.
    Swan C (1964) A neurilemmoma of the choroid. Med J Austr 1: 677–678Google Scholar
  28. 28.
    Trevor-Roper PD (1944) Case of neurofibroma of the choroid. Br J Ophthalmol 28: 177–180Google Scholar
  29. 29.
    Vannas S, Raitta C, Tarkkanen A (1974) Neurilemmoma of the choroid in Recklinghausen's disease. Acta Ophthalmol [Suppl] 123: 126–133Google Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • Thierry J. Hufnagel
    • 1
  • Marvin L. Sears
    • 2
  • Marc Shapiro
    • 3
  • Jung H. Kim
    • 1
  1. 1.Section of Neuropathology, Department of SurgeryYale University School of MedicineNew HavenUSA
  2. 2.Department of Ophthalmology and Visual SciencesYale University School of MedicineNew HavenUSA
  3. 3.Section of Neuroradiology, Department of Diagnostic ImagingYale University School of MedicineNew HavenUSA

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