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The prevention of an acute rise in intraocular pressure following Q-switched Nd:YAG laser iridotomy with clonidine

  • Clinical Investigations
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Abstract

We evaluated the ability of topical clonidine to suppress an acute rise in postoperative intraocular pressure (IOP) following Nd:YAG laser iridotomy. A total of 36 eyes (29 patients) with chronic primary angle-closure glaucoma underwent Q-switched Nd:YAG laser iridotomy: 18 eyes were treated topically with 0.5% clonidine ophthalmic solution prior to and immediately following the procedure, and a control group of 18 eyes underwent Nd:YAG laser iridotomy without topical clonidine. The control group was selected to match the clonidine-treated group in terms of preoperative IOP, the extent of peripheral anterior synechia, and the total amount of laser energy delivered. None of the clonidine-treated eyes experienced an IOP rise greater than 4 mm Hg over baseline, wereas 4 of the nontreated eyes (22.2%) developed an IOP rise greater than 10 mm Hg. The mean IOPs were significantly lower during the first 4 h postsurgery in the clonidine-treated eyes.

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Authors and Affiliations

  1. Department of Ophthalmology, Gifu University School of Medicine, 40 Tsukasa-machi, Gifu-shi, 500, Japan

    Yoshiaki Kitazawa, Kazuhisa Sugiyama & Tohru Taniguchi

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  1. Yoshiaki Kitazawa
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  2. Kazuhisa Sugiyama
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  3. Tohru Taniguchi
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Kitazawa, Y., Sugiyama, K. & Taniguchi, T. The prevention of an acute rise in intraocular pressure following Q-switched Nd:YAG laser iridotomy with clonidine. Graefe's Arch Clin Exp Ophthalmol 227, 13–16 (1989). https://doi.org/10.1007/BF02169817

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  • DOI: https://doi.org/10.1007/BF02169817

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