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The preparation of astatine labelled tyrosine using an electrophilic reaction

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Abstract

Carrier-free astatotyrosine has been synthesized using an electrophilic reaction in acidic media. Temperature of 150–160°C and reaction time of 20–30 min were chosen as optimal conditions for the synthesis of astatotyrosine. Under the selected conditions the yield was about 90%.

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Authors and Affiliations

  1. Joint Institute for Nuclear Resarch, Dubna, USSR

    Yu. V. Norseyev, D. D. Nhan, V. A. Khalkin & N. Q. Huan

  2. Central Research Institute for Physics, Budapest, Hungary

    L. Vasaros

Authors
  1. Yu. V. Norseyev
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  2. D. D. Nhan
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  3. V. A. Khalkin
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  4. N. Q. Huan
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  5. L. Vasaros
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Norseyev, Y.V., Nhan, D.D., Khalkin, V.A. et al. The preparation of astatine labelled tyrosine using an electrophilic reaction. Journal of Radioanalytical and Nuclear Chemistry Letters 94, 185–190 (1985). https://doi.org/10.1007/BF02167979

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  • DOI: https://doi.org/10.1007/BF02167979

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