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The deuteration of p-substituted phenylalanines

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Abstract

The isotope exchange between substituted /p-OH, p-CH3O, p-C2H5O, H, p-NO2/ phenylalanines and deuterated water in the presence of K2PtCl4 as a catalyst was studied. It was found that isotope exchange is centered in the aromatic ring, in the methoxy and methyl groups. Electron donating groups accelerate the reaction and electron with-drawing groups retard it.

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Authors and Affiliations

  1. Laboratory of Peptides, Department of Chemistry, Warsaw University, Pasteura 1, 02-093, Warsaw, Poland

    M. Kanska

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  1. M. Kanska
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Kanska, M. The deuteration of p-substituted phenylalanines. Journal of Radioanalytical and Nuclear Chemistry Letters 87, 95–100 (1984). https://doi.org/10.1007/BF02167674

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  • DOI: https://doi.org/10.1007/BF02167674

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