Summary
Using paper electrophoresis, the author found that when human hemoglobin is added to human sera, it is captured by a fraction of theα 2-globulin, which results in a compound with an electrophoretic mobility between that ofα 2-globulin andβ-globulin.
He identifies this fraction of theα 2-globulin with the haptoglobin discovered byJayle. This phenomenon may influence the estimation ofα 2-globulin even in slightly hemolytic sera.
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References
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A. H. H. van Royen dansL. W. Jansen:Electrophoretic studies on serum proteins (1951), p. 94.
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Wieme, R.J. La migration de l'hémoglobine additionnée au sérum humain lors de l'électrophorèse sur papier. Experientia 9, 380–381 (1953). https://doi.org/10.1007/BF02167643
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DOI: https://doi.org/10.1007/BF02167643