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Über die Ausscheidung und Speicherung von radioaktiv indizierten Xylanschwefelsäureestern

II. Dauer der speicherung, Kumulierung, Vergleich mit Heparin

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Summary

The storage of anticoagulant Xylane sulfuric acid esters, as tested by the radioactivity of compounds containing S35, is of an extremely long duration. After three weeks the quantity found in the liver is the same as that found after 48 h. Additional dosage results in further accumulation. Heparin is no exception since it behaves as Xylane sulfuric acid ester of the same viscosity and sulfur content.

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References

  1. E. Husemann, E. G. Hoffmann, R. Lötterle undM. Wiedersheim, Exper.8, 153 (1952).

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  2. E. G. Hoffmann, E. Husemann, R. Lötterle, M. Wiedersheim undW. Hertlein,Makromolekulare Chemie (im Druck).

  3. Nach osmotischen Messungen vonB. Pfannemüller liegt derKm-Wert bei 3·10−4. Die bei der 1. Mitteilung mit 6,2 berechneten Polymerisationsgrade sind also entsprechend umzurechnen.

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Authors and Affiliations

  1. Aus dem Staatlichen Forschungsinstitut für makromolekulare Chemie und dem Pharmakologischen Institut der Universität Freiburg i. Br., Germany

    E. Husemann, B. Pfannemüller & W. Hertlein

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  1. E. Husemann
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  2. B. Pfannemüller
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  3. W. Hertlein
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Husemann, E., Pfannemüller, B. & Hertlein, W. Über die Ausscheidung und Speicherung von radioaktiv indizierten Xylanschwefelsäureestern. Experientia 9, 379–380 (1953). https://doi.org/10.1007/BF02167642

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  • DOI: https://doi.org/10.1007/BF02167642

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