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Über einen Cortison-äquivalenten Katalysator der Autoxydation der Linolsäurein vitro

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Summary

Acetophenone derivatives with a cortisone-like side chain have been investigated for their catalytic effect on the autoxydation of linolenic acid.ω-Hydroxy-acetophenone and the substitutedω-hydroxy-3,4-dimethoxyacetophenone are the substances with the simplest structure having a catalytic effect quantitatively and qualitatively similar to that of cortisone.

The significance of substituents in the ring for the catalytic activity of the side chain is discussed.

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Authors and Affiliations

  1. Forschungslaboratorien der CIBA Aktiengesellschaft, Basel, Pharmazeutische Abteilung, Switzerland

    W. Schuler & R. Meier

Authors
  1. W. Schuler
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  2. R. Meier
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Schuler, W., Meier, R. Über einen Cortison-äquivalenten Katalysator der Autoxydation der Linolsäurein vitro. Experientia 14, 288–289 (1958). https://doi.org/10.1007/BF02167003

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  • DOI: https://doi.org/10.1007/BF02167003

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