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Purin- und Pyrimidinbasen der Desoxyribonukleinsäure des Ehrlichschen Mäuse-Ascites-Karzinomas

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Summary

The proportion of purines and pyrimidines in the DNA of the Ehrlich mouse ascites carcinoma is examined and compared with the base proportion of the DNA from liver and kidney of the normal mouse. The following findings were obtained: The DNA of the ascites tumor contains more guanine and less cytosine and thymine than the DNA of the normal mouse. For guanine this difference is statistically significant. The changed base compound is discussed with regard to the changed growing rate in tumors and the altered chromosome structure in the Ehrlich ascites carcinoma.

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Authors and Affiliations

  1. Universitäts-Frauenklinik Heidelberg, Germany

    W. Schneider & H. Ebner

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  1. W. Schneider
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  2. H. Ebner
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Durchgeführt mit Unterstützung der Deutschen Forschungsgemeinschaft.

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Schneider, W., Ebner, H. Purin- und Pyrimidinbasen der Desoxyribonukleinsäure des Ehrlichschen Mäuse-Ascites-Karzinomas. Experientia 11, 491–493 (1955). https://doi.org/10.1007/BF02166835

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  • DOI: https://doi.org/10.1007/BF02166835

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