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Experientia

, Volume 7, Issue 3, pp 81–89 | Cite as

Oxydations microbiennes des stéroïdes

  • Carlo Arnaudi
Article

Summary

The author discusses the opinions set forth by several authors upon the behaviour of bacteria towards steroids. He examines particularly their behaviour in respect to the resistance of cholesterol against attack by microbes and the antibacteric action of many substances having the phenanthrene nucleus in common.

The author describes his experiences in regard to the oxidation of steroids explaining hormonal activity; he reports the most important characteristics of the various bacteria and also the conditions at which oxidation takes place.

Furthermore he describes the most recent knowledges about the oxidative transformation of cholesterol.

Afterwards he examines the functions of many active organisms (Flavobacterium, Proactinomyces, Mycobacterium), the modalities of oxidation, the evolution of the process, and the products resulting from oxidation.

At last the author recalls the decisive influence exercised by the chemical composition of the substrate in which cholesterol is suspended upon the process, which can evolve into a complete demolition of the molecule or to a selective oxidation with production of substances that still retain the fundamental structure of steroids.

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Copyright information

© Birkh\:auser Verlag 1951

Authors and Affiliations

  • Carlo Arnaudi
    • 1
  1. 1.Institut de Microbiologie générale, agricole et technique de l'Université de MilanItaly

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