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Konfiguration des Periplogenins undallo-Periplogenins

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Summary

By means of reactions which proceed without isomerization at C-3 and C-17, it has been possible to break down periplogenin into the known 3β-acetoxy-etio-allo-cholanic-acid-methylester. In consideration of this fact together with other known and unpublished findings it is very probable that all functional groups in periplogenin are arranged in theβ-configuration. The same breaking-down when applied to the biologically inactiveallo-periplogenin produced the known 3β-acetoxy-14-iso-17-iso-etio-allo-cholanicacid-methylester.Allo-periplogenin is distinguished from periplogenin by the stereoconfiguration at position 17.

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Authors and Affiliations

  1. Pharmazeutische Anstalt der Universität Basel, Switzerland

    F. Speiser & T. Reichstein

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  1. F. Speiser
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  2. T. Reichstein
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Die ausführliche Publikation erscheint in den Helv. chim. Acta.

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Speiser, F., Reichstein, T. Konfiguration des Periplogenins undallo-Periplogenins. Experientia 3, 323–324 (1947). https://doi.org/10.1007/BF02164245

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  • DOI: https://doi.org/10.1007/BF02164245

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