Summary
The growth factors for microorganisms are nothing else than the vitamines known in animal physiology. Some microorganisms, like animals, have lost the possibility of synthetising these factors, which must be added to the culture medium. The action of the vitamine is quantitative and specific. These properties enable the auxo-heterotrophic microorganism, having lost the possibility of synthesis for a determined vitamine, to be used for a quantitative determination of this factor. The Phycomyces test for thiamine (vitamine B1) and its different practical applications are discussed.
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Schopfer, W.H. Les tests microbiologiques pour la détermination des vitamines. Experientia 1, 183–194 (1945). https://doi.org/10.1007/BF02164064
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DOI: https://doi.org/10.1007/BF02164064