Skip to main content
SpringerLink
Log in

Biological and radiochemical quality control of indigenous99mTc-radiopharmaceutical kits

  • Published:
Journal of Radioanalytical and Nuclear Chemistry Aims and scope Submit manuscript

Abstract

Biological and radiochemical quality control of indigenous (Pinscan) diagnostic cold kits of Methylene Diphosphonate (MDP), Tin-colloid and Diethylene Triamine Pentaacetic Acid (DTPA) was performed in parallel with imported Amersham's kits (Amerscan). The results of radiochemical purity, sterility, apyrogenicity and biodistribution of indigenous (Pinscan) kits were good and quantitatively and qualitatively comparable to those obtained with Amersham's (Amerscan) imported kits.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. R. S. Mani, N. G. S. Gopal, Industrial Production of Radiopharmaceuticals in: Radiopharmacy. (Eds by M. Tubis and W. Wolf), John Wiley and Sons, New York, 1976, p. 507.

    Google Scholar 

  2. World Health Organization, Quality Assurance in Nuclear Medicine, Geneva, 1982.

  3. P. Gertrude,Nuklearmedizin, 23 (1984) 4.

    PubMed  Google Scholar 

  4. K. Kristensen, E. Norbygaord, Safety and Efficacy of Radiopharmaceuticals, Martins Nijhoff Publishers, Boston, 1984.

    Google Scholar 

  5. Analytical Quality Control of Radiopharmaceuticals, Proceeding of Panel of IAEA, 1970.

  6. E.D. William, L.K. Harding, J.H. Mckillop,Nucl. Med. Comm., 10 (1989) 595.

    Google Scholar 

  7. Preparation of Kits of99mTc-Radiopharmaceuticals, IAEA-TECDOC-649, May 1992.

  8. G.B. Saha, Fundamentals of Nuclear Pharmacy, Springer Verlag, New York, 1984.

    Google Scholar 

  9. S.M. Karesh,J. Nucl. Med. Tech., 3 (1989) 156.

    Google Scholar 

  10. S.J. Khurshid, H.M.A. Karim, Biological Quality Control of Radiopharmaceuticals, PINSTECH/NCD-(23), 1981.

  11. S.J. Khurshid,J. Pak. Med. Assoc., (in press).

  12. S.J. Khurshid, B. Shahnaz, Radiometric Sterility Testing of Radiopharmaceuticals, H. NCD/P-101, 1988.

  13. H. Murrata, M. Kobayashi, M. Lio, H. Yamada, K. Chiba, K. Matsui, S. Kawaguchi,J. Nucl. Med., 17 (1976) 1088.

    PubMed  Google Scholar 

  14. Z.H. Oster, et. al.: The Role of Analysis in the Evaluation of Radiopharmaceuticals Nuclear Medical Biology, 16:85. 1989.

    Google Scholar 

  15. P.J. Robin, Chromatography of99mTc-Radiopharmaceuticals: A Practical Guide, The Society of Nuclear Medicine, Inc., New York, 1986.

    Google Scholar 

  16. A.M. Millar,Nucl. Med. Comm., 4 (1983) 368.

    Google Scholar 

  17. V. Jovanovie, D. Konstanitinovska, T. Memedovie,Eur. J. Nucl., 6 (1981) 175.

    Google Scholar 

  18. A.M. Millar, J.J.K. Best, M.V. Merrick, A.L. Muir,Nucl. Med. Comm., 2 (1981) 147.

    Google Scholar 

  19. A.J. Tofe, J.A. Bevan,J. Nucl. Med., 21 (1980)

  20. R.W. Beightol, J. Cochrane,J. Nucl. Med. Tech., 11 (1983) 173.

    Google Scholar 

  21. O.W. Krogsgaard,Eur. J. Nucl. Med., 1 (1976) 15.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Centre for Nuclear Studies, PINSTECH, P.O. Nilore, Islamabad, Pakistan

    M. B. Imran

  2. Nuclear Chemistry Division, PINSTECH, P.O. Nilore, Islamabad, Pakistan

    S. J. Khurshid & H. M. A. Karim

Authors
  1. M. B. Imran
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. J. Khurshid
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. M. A. Karim
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Imran, M.B., Khurshid, S.J. & Karim, H.M.A. Biological and radiochemical quality control of indigenous99mTc-radiopharmaceutical kits. Journal of Radioanalytical and Nuclear Chemistry Letters 176, 211–223 (1993). https://doi.org/10.1007/BF02163672

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02163672

Keywords

Search

Navigation