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Journal of Radioanalytical and Nuclear Chemistry

, Volume 214, Issue 6, pp 499–508 | Cite as

Preparation of99mTc-thiourea complex as a precursor for Tc(III) labeled compounds

  • A. Rey
  • M. Terán
  • C. Kremer
  • S. Molina
  • D. Gambino
  • E. Kremer
  • A. León
Article

Abstract

Ligand exchange is one of the possible synthetic routes to obtain99mTc coordination compounds. However, the success of this route depends on the availability of good precursors. The objective of this work is the preparation of the complex [99mTc(tu)6]3+ (tu = thiourea), as a potential precursor for99mTc(III) coordination compounds. The preparation was successfully performed in acidic conditions, the excess of tu serving as reducing agent. At pH values higher than 3, the compound becomes unstable and on addition of polydentate ligands new Tc(III) complexes are formed. With edta, the complex99mTc(III)-edta was obtained in high yield.

Keywords

Physical Chemistry Edta Inorganic Chemistry Thiourea Acidic Condition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Akadémiai Kiadó 1996

Authors and Affiliations

  • A. Rey
    • 1
  • M. Terán
    • 1
  • C. Kremer
    • 2
  • S. Molina
    • 1
  • D. Gambino
    • 2
  • E. Kremer
    • 2
  • A. León
    • 1
  1. 1.Cátedra de Radioquímica, Facultad de QuímicaMontevideoUruguay
  2. 2.Cátedra de Química Inorgánica, Facultad de QuímicaMontevideoUruguay

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