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Design of a fast method to produce14C-labeled carboxylic acids

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Abstract

An efficient method to produce [1-14C] benzoic acid within a total time less than 20 min in high chemical and radiochemical yield is described. The procedure we report can be applied for the preparation of [11C]-labeled carboxylic acids suitable for evaluation in the study of human metabolism by positron emission tomography.

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Authors and Affiliations

  1. Department of Radioactive Materials, Instituto Nacional de Investigaciones Nucleares, Sierra Mojada 447 Lomas de Barrilaco, C.P. 11010, México, D.F., Mexico

    G. Ferro-Flores

  2. Department of Radioisotopes, Japan Atomic Energy Research Institute, Tokai-mura, 319-11, Naka-gun, Ibaraki-ken, Japan

    F. Miura, H. Matsuoka & K. Hoizumi

Authors
  1. G. Ferro-Flores
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  2. T. Moriya
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  3. F. Miura
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  4. H. Matsuoka
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  5. K. Hoizumi
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Ferro-Flores, G., Moriya, T., Miura, F. et al. Design of a fast method to produce14C-labeled carboxylic acids. Journal of Radioanalytical and Nuclear Chemistry Letters 175, 219–228 (1993). https://doi.org/10.1007/BF02163347

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  • DOI: https://doi.org/10.1007/BF02163347

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