Journal of Radioanalytical and Nuclear Chemistry

, Volume 119, Issue 4, pp 263–273 | Cite as

99mTc complexes of 1,3-propanedithiol derivatives

  • A. Alagui
  • M. Apparu
  • A. Bardy
  • J. P. Mathieu
  • M. Vidal
Article

Abstract

The labelling of 1,3-n alkylpropanedithiols and of 15-/1,3-dimercapto 2-propyl/ pentadecanoic acid by99mTc has been performed by an exchange reaction with the hexachlorotechnetate ion99mTcCl 6 2− and by reduction of99mTcO 4 with Sn/II/ in the presence of the ligand. The biological distribution of the exotechnetium complexes obtained by the latter method in mouse does not reveal a high tropism of these labelling compounds in relation to a particular tissue.

Keywords

Physical Chemistry Inorganic Chemistry Exchange Reaction Labelling Compound Pentadecanoic Acid 

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Copyright information

© Akadémiai Kiadó 1987

Authors and Affiliations

  • A. Alagui
    • 1
  • M. Apparu
    • 1
  • A. Bardy
    • 2
  • J. P. Mathieu
    • 3
  • M. Vidal
    • 1
  1. 1.Laboratoire d'Etudes Dynamiques et Structural de la Séléctivité /LEDSS IV/Université de Grenoble /USTMG/St Martin d'HeresFrance
  2. 2.Compagnie ORIS Industrie SA, SaclayGif-Sur-YvetteFrance
  3. 3.Laboratoire d'Etude des Radiopharmaceutiques-BiophysiqueFaculté de Médicine de GrenobleLa TroncheFrance

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