Summary
The author has studied some details of the passage of saline through connective membranes of normal albino young rats. A mucopolysaccharide is present in such membranes which can be removed soon after addition of hyaluronidase and, at a much slower rate, by the mere passage of fluids through the tissue. Such mucopolysaccharide, most likely hyaluronic acid, seems to be present in quantities not too different from one membrane to another and it appears to be bound to some other tissue microstructure by means of rather loose chemical bonds. Once the mucopolysaccharide removed, the hydration of some other substrate probably takes place, thus causing the free interstices to get narrower with consequent decrease in the flowing velocity of the saline.
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Benassi, G. Sul comportamento della sostanza fondamentale in membrane connettivali di ratto albino durante il passaggio di una soluzione salina. Experientia 11, 102–103 (1955). https://doi.org/10.1007/BF02161691
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DOI: https://doi.org/10.1007/BF02161691