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Studies on organic fluorine compounds II

Esters of oxalofluoroacetic acid

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Résumé

Les esters éthyliques et tertiobutyliques ont été synthétisés à partir des esters correspondants de l'acide oxalique et fluoroacétique par une condensation de Claisen Wislicenus.

En injection intrapéritonéale effectuée sur des souris et des rats, ces esters se sont montrés pratiquement non toxiques. En revanche, ils exercent (sous forme d'énolates sodiques hydro-solubles) une action inhibitrice prononcée sur la croissance de l'Escherichia coli etAerobacter aerogenes dans des milieux de cultures synthétiques.

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Authors and Affiliations

  1. Israeli Institute for Biological Research, Ness-Ziona, Israel

    I. Blank & J. Mager

Authors
  1. I. Blank
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  2. J. Mager
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Additional information

Part I:E. Bergmann andI. Blank, J. chem. Soc., in press (1953).

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Blank, I., Mager, J. Studies on organic fluorine compounds II. Experientia 10, 77–78 (1954). https://doi.org/10.1007/BF02161466

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  • DOI: https://doi.org/10.1007/BF02161466

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