Summary
A series of demecolceinamids was examinedin vitro on chicken fibroblasts, leucocytes, and different bacteria. It was found that with increasing length of the side chain on ring C the antimitotic activity is decreasing while the antibacterial effect is increasing.
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References
F. Šantavy, D. Lang undB. Malinsky, Arch. int. Pharmacodyn.84, 257 (1950).
F. Šantavy, R. Winkler undT. Reichstein, Helv. chim. Acta36, 1319 (1953).
A. Uffer, O. Schindler, F. Šantavy undT. Reichstein, Helv. chim. Acta37, 18 (1954).
A. Uffer, Exper.10, 76 (1954).
B. Schär, P. Loustalot undF. Gross, Klin. Wo.32, 49 (1954).
H. Lettré, Angew. Chemie63, 421 (1952).
R. Meier undB. Schär, Exper.7, 308 (1951).
L. Neipp, Schweiz. Z. Path. Bakt.9, 66 (1946).
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Meier, R., Schär, B. & Neipp, L. Die Wirkung von Demecolceinamiden an Zellenin vitro. Experientia 10, 74–76 (1954). https://doi.org/10.1007/BF02161464
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DOI: https://doi.org/10.1007/BF02161464