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Reaktivierung zwischen Vaccine- und Variolavirus

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Zeitschrift für Hygiene und Infektionskrankheiten, medizinische Mikrobiologie, Immunologie und Virologie Aims and scope Submit manuscript

Zusammenfassung

Variolavirus reaktivierte wärmeinaktiviertes Vaccinevirus in HeLa-Zellkulturen, auf der CAM des bebrüteten Hühnereies und nach i.cer. Impfung der infantilen Maus. Die umgekehrte Reaktivierung von inaktiviertem Variolavirus mit vermehrungsfähigem Vaccinevirus konnte nur in HeLa-Kulturen nachgewiesen werden. Versuche an i.p. infizierten Babymäusen und intracutan geimpften Kaninchen verliefen negativ. Veränderungen der für das bebrütete Hühnerei charakteristischen Merkmale beider Viren wurden bei den Reaktivierungen nicht beobachtet.

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Authors and Affiliations

  1. Bundesforschungsanstalt für Viruskrankheiten der Tiere, Tübingen

    Helmut Mahnel

  2. Bayerischen Landesimpfanstalt München, Deutschland

    Helmut Mahnel

Authors
  1. Helmut Mahnel
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Additional information

Herrn Professor Dr. A.Herrlich zum 60. Geburtstag gewidmet.

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Mahnel, H. Reaktivierung zwischen Vaccine- und Variolavirus. Zeitschr. f. Hygiene. 148, 296–306 (1962). https://doi.org/10.1007/BF02161325

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  • DOI: https://doi.org/10.1007/BF02161325

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