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Experientia

, Volume 11, Issue 5, pp 175–177 | Cite as

The steric course of hydrogenation of Δ4 and Δ5 steroids

  • H. I. Hadler
Kurze Mitteilungen

Keywords

Hydrogenation Steroid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Bei der katalytischen Hydrierung von Steroiden mit Doppelbindung in 4-Stellung entstehen überwiegend A/B-cis-Verbindungen, während Doppelbindung in 5 vor allem A/B-trans liefert. Dieser Unterschied wird mit Hilfe der Konstellationsanalyse erklärt: die als Zwischenformen angenommenen Komplexe aus Substrat, Wasserstoff und Katalysator weisen unterschiedliche sterische Hinderung auf.

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Copyright information

© Birkhäuser Verlag 1955

Authors and Affiliations

  • H. I. Hadler
    • 1
  1. 1.Division of OncologyThe Chicago Medical SchoolChicago 8

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