, Volume 17, Issue 5, pp 211–212 | Cite as

Release of histamine by cotton dust extracts from human lung tissuein vitro

  • A. Bouhuys
  • S. -E. Lindell
Kurze Mitteilungen


Dust Histamin Human Lung Cotton Dust Dust Extract 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Baumwollextrakt, bei 37° mit zerkleinertem menschlichem Lungengewebe inkubiert, setzt daraus Histamin in ähnlichen Mengen wie Compound 48/80 frei.

Die Ergebnisse stützen die Hypothese, dass die Symptome der Byssinosis bei Baumwollspinnerei-Arbeitern mindestens teilweise durch eine Histamin-freisetzende Substanz im Baumwollstaub verursacht werden.


  1. 1.
    A. Bouhuys, S.-E. Lindell, andG. Lundin, Medical Research Councils Panel on Byssinosis, June 4th (1959).Google Scholar
  2. 2.
    A. Bouhuys, S.-E. Lindell, andG. Lundin, Brit. Med. J.i, 324 (1960).Google Scholar
  3. 3.
    H. Antweiler, Naturwiss.46, 493 (1959).CrossRefGoogle Scholar
  4. 4.
    H. Antweiler, Arch. Gewerbepath. Gewerbehyg.17, 574 (1960).CrossRefGoogle Scholar
  5. 5.
    W. D. M. Paton, Pharmacol. Rev.9, 269 (1957).PubMedGoogle Scholar
  6. 6.
    B. Diamant, X. Scandinavian Physiol. Congr. in Oslo (1960), p. 34.Google Scholar
  7. 7.
    J. L. Mongar andH. O. Schild, Brit. J. Pharmacol.8, 103 (1953).PubMedGoogle Scholar
  8. 8.
    J. L. Mongar andH. O. Schild, J. Physiol.118, 461 (1952).PubMedGoogle Scholar
  9. 9.
    B. Lilja, S.-E. Lindell, andT. Saldéen, J. Allergy31, 492 (1960).CrossRefPubMedGoogle Scholar
  10. 10.
    C. Prausnitz, Medical Research Council Report:Investigations on Respiratory Dust Diseases in Operatives in the Cotton Industry. H. M. Stationery Office (1936).Google Scholar
  11. 11.
    E. Haworth andA. D. McDonald, J. Hyg.37, 234 (1937).Google Scholar
  12. 12.
    The authors thank ProfessorA. G. Brom (Leiden) and DocentN. P. Berg (Gothenburg) for their help in making surgical specimens of lung tissue available, Dr.L. Muller (Enschede) for supplying samples of cotton dust, and MissM.-B. Johansson for valuable technical assistance. This work was supported in part by research grants to one of us (A.B.) from the ‘Organisation for Health Research T.N.O.’ (The Hague) and the ‘Foundation for the Advancement of Medical Scientific Research’ (Arnhem).Google Scholar

Copyright information

© Birkhäuser Verlag 1961

Authors and Affiliations

  • A. Bouhuys
    • 1
    • 2
  • S. -E. Lindell
    • 1
    • 2
  1. 1.Laboratory of Clinical PhysiologyUniversity HospitalLeidenThe Netherlands
  2. 2.Laboratory of Clinical Physiology, Sahlgrenska SjukhusetGöteborgSweden

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