Skip to main content
Log in

The effect of glycerol on the biosynthesis of benzylpenicillin by the washed cells of

Penicillium chrysogenum

  • Kurze Mitteilungen
  • Published:
Experientia Aims and scope Submit manuscript

Résumé

Les auteurs ont trouvé que le glycérol active la biosynthèse de la benzylpénicilline obtenue par des cellules lavées deP. chrysogenum suspendues dans un tampon de phosphate et d'acétate de phényle. Le lactate, le pyruvate, le citrate, le malate et le succinate n'ont été d'aucun effet. Le dinitrophénol, le cyanide et l'arsénite inhibent la biosynthèse de la pénicilline à un degré variable dans le milieu PA plus glycérol, aux concentrations de 0,0006M, 0,005M et 0,0005M respectivement.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. V. N. Deshpande andK. Ganapathi, Exper.13, 475 (1957); J. sci. industr. Res. (India),17 C, 59 (1958).

    CAS  Google Scholar 

  2. M. Somogyi, J. biol. Chem.195, 19 (1952).

    Article  CAS  Google Scholar 

  3. F. J. Ryley, Biochem. J.59, 353 (1955).

    Article  CAS  Google Scholar 

  4. B. L. Horecker, Brewers Digest28, 214 (1953).

    Google Scholar 

  5. L. I. Gidez andM. L. Karnosvky, J. biol. Chem.206, 229 (1954).

    Article  CAS  Google Scholar 

  6. P. Schambye, H. G. Wood, andG. Popjak, J. biol. Chem.206, 875 (1954).

    Article  CAS  Google Scholar 

  7. R. W. Swick andA. Nakao, J. biol. Chem.206, 883 (1954).

    Article  CAS  Google Scholar 

  8. G. Hauser andM. L. Karnovsky, J. biol. Chem.224, 91 (1957).

    Article  CAS  Google Scholar 

  9. J. G. Hauge, T. E. King, andV. H. Cheldelin, J. biol. Chem.214, 11 (1955).

    Article  CAS  Google Scholar 

  10. B. C. Sison andW. J. Schubert, Nature181, 1015 (1958).

    Article  CAS  Google Scholar 

  11. J. McCorkindale andN. L. Edson, Biochem. J.57, 518 (1954).

    Article  CAS  Google Scholar 

  12. B. L. Horecker andA. H. Mehler, Ann. Rev. Biochem.24, 243 (1955).

    Article  Google Scholar 

  13. T. Mann andI. G. White, Nature178, 142 (1956).

    Article  CAS  Google Scholar 

  14. Y. J. Topper andA. B. Hastings, J. biol. Chem.179, 1255 (1949).

    Article  CAS  Google Scholar 

  15. H. Krebs, Johns Hopk. Hosp. Bull.95, 19 (1954).

    CAS  Google Scholar 

  16. V. N. Deshpande andK. Ganapathi, unpublished observations.

  17. G. N. Rolinson, J. gen. Microbiol.11, 412 (1954).

    Article  CAS  Google Scholar 

  18. W. J. Halliday andH. R. V. Arnstein, Biochem. J.64, 380 (1956).

    Article  CAS  Google Scholar 

  19. R. J. Anderson, E. G. H. Tornquist, andW. H. Peterson, Agric. Food Chem.4, 556 (1955).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Irani, R.J., Ganapathi, K. The effect of glycerol on the biosynthesis of benzylpenicillin by the washed cells of. Experientia 14, 329–330 (1958). https://doi.org/10.1007/BF02160390

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02160390

Keywords

Navigation