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Effect of single and chronic thyroxine injection on fatty acid and cholesterol synthesis in mice

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Résumé

L'effet d'une dose souscutanée de 1-Thyroxine sur des souris à jeun consiste en une augmentation progressive de la lipogénèse et de la cholestérogénèse hépatiques. Cette augmentation atteint 70% pour la lipogénèse après 24 h et 300–500% pour la cholesterogénèse après 24, 36 et 48 h.

Un traitement chronique (28 j) cause une augmentation (400%) de la lipogénèse, mais non de la cholestérogénèse hépatiques.

Les effets de la thyroxine sur la lipogénèse et la cholestérogénèse extra-hépatiques sont beaucoup moins nets.

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References

  1. M. A. Spirtes, G. Medes, andS. Weinhouse, J. biol. Chem.204, 705 (1953).

    Article  CAS  Google Scholar 

  2. R. H. Rosenman, S. O. Beyers, andM. Friedman, J. clin. Endocrin.12, 1287 (1952).

    Article  CAS  Google Scholar 

  3. W. Marx, S. T. Gustin, andC. Levi, Proc. Soc. exp. Biol. Med., N.Y.83, 143 (1953).

    Article  CAS  Google Scholar 

  4. M. A. Spirtes, G. Medes, andS. Weinhouse, XIXth Intern. Physiol. Congr. Abstr. Montreal (1953), p. 789.

  5. C. E. Zomzely andJ. Mayer, Amer. J. Physiol.187, 365 (1956).

    Article  CAS  Google Scholar 

  6. C. E. Zomzely andJ. Mayer, Amer. J. Physiol.196, 956 (1959).

    Article  CAS  Google Scholar 

  7. S. D. Burton, E. D. Robbins, andS. O. Beyers, Proc. Soc. exp. Biol. Med., N. Y.92, 272 (1956).

    Article  CAS  Google Scholar 

  8. G. E. Glock, P. McLean, andJ. K. Whitehead, Biochem. J.63, 520 (1956).

    Article  CAS  Google Scholar 

  9. G. E. Glock andP. McLean, Biochem. J.61, 390 (1955).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Harvard School of Public Health, USA

    Paola Marchi (Holder of a Research Fellowship in Department of Nutrition)

  2. Department of Nutrition, Harvard School of Public Health, Boston, Mass.

    J. Mayer

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  1. Paola Marchi
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  2. J. Mayer
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Additional information

Supported in part by grants-in-aid from the John A. Hartford Memorial Fund; the National Institute of Arthritis and Metabolism (Gr. No. A-49) Public Health Service, Bethesda; the Albert and Mary Lasker Foundation, New York; the Nutrition Foundation, New York; and the Fund for Research and Teaching, Dept. of Nutrition, Harvard.

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Marchi, P., Mayer, J. Effect of single and chronic thyroxine injection on fatty acid and cholesterol synthesis in mice. Experientia 15, 359–361 (1959). https://doi.org/10.1007/BF02159833

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