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Experientia

, Volume 14, Issue 3, pp 88–89 | Cite as

Microbiological hydroxylation of certain indole alkaloids

  • W. O. Godtfredsen
  • G. Korsby
  • H. Lorck
  • S. Vangedal
Kurze Mitteilungen

Keywords

Alkaloid Indole Indole Alkaloid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Zusammenfassung

Aerobe Kulturen vonCunninghamella Blakesleana Lendner hydroxylieren Apoyohimbin,β-Yohimbinmethyläther und 3-Epiapoyohimbin in der 10-Stellung. Aus Apoyohimbin wurde auch ein zweites Umwandlungsprodukt erhalten, vermutlich 18-Hydroxyapoyohimbin.

References

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    G. Barger andE. Field, J. chem. Soc.123, 1038 (1923)Google Scholar
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    W. O. Godtfredsen andS. Vangedal, Acta chem. Scand.11, 1013 (1957).Google Scholar
  3. 4.
    W. O. Godtfredsen undS. Vangedal, Acta chem. Scand.10, 1414 (1956).Google Scholar
  4. 5.
    W. O. Godtfredsen andS. Vangedal, Acta chem. Scand.11, 1013 (1957);10, 1414 (1956).Google Scholar
  5. 5a.
    I. E. Bush, Biochem. J.50, 370 (1952).PubMedGoogle Scholar
  6. 6.
    For details, seeR. J. Block, E. L. Durrum, andG. Zweig,Paper Chromatography (Academic Press, N.Y. 1955), p. 95.Google Scholar
  7. 7.
    A similar hydroxylation is the recently reported conversion of tryptophan withChromobacterium violaceum: C. Mitoma, H. Weissbach, andS. Udenfriend, Arch. Biochem. Biophys.63, 122 (1956).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1957

Authors and Affiliations

  • W. O. Godtfredsen
    • 1
  • G. Korsby
    • 1
  • H. Lorck
    • 1
  • S. Vangedal
    • 1
  1. 1.Research DepartmentLeo Pharmaceutical Products CopenhagenDenmark

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