Summary
The described antiphage substance: bis-[[4-[4-(3-diethylamino-propylamino)-6-methyl-2-pyrimidyl-amino]-phenyl]]-sulphone tetrahydrochloride tetrahydrate produces its effect not through a direct phagocytic action but indirectly through an inhibition of the phage production. The effect is complete during the whole logarithmic growth phase as long as the phage concentration is kept under the limit, critical for bacteriolysis.
Literatur
L. Neipp, W. Kunz undR. Meier, Exper.13, 74 (1957).
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Meier, R., Neipp, L. & Kunz, W. Eintritt und Mechanismus phagenhemmender Wirkungen. Experientia 14, 364–366 (1958). https://doi.org/10.1007/BF02159157
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DOI: https://doi.org/10.1007/BF02159157