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Uncoupling of the disorder of carbohydrate metabolism from fat metabolism in experimentally-produced diabetes in baboons(Papio ursinus)

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Résumé

Après ablation de la glande pituitaire, ledérèglement du du métabolisme des hydrates de carbone persiste, tandis que l'intense lipémie est abolie. L'administration de la cortisone aux babouins pancréas- et hypophysectomisés privés d'insuline, rétablit la lipémie mais non la cétonémie.

Le dérèglement du métabolisme des hydrates de carbone dans les babouins diabétiques peut être dissocié de celui des lipides par un traitement approprié des glandes endocrines.

La cétonémie des babouins pancréas- et hypophysectomisés, contrairement à la lipémie, n'est pas rétabli par l'administration de la cortisone, thyroxin ou par une combinaison de ces hormones.

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References

  1. C. N. H. Long andF. D. W. Lukens, J. exp. Med.63, 465 (1936).

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Authors and Affiliations

  1. Departments of Physiology and Anatomy and Joint Nutrition Research Unit of the C.S.I.R. and of the University of the Witwatersrand, Johannesburg

    E. Epstein

  2. Department of Surgery, University of the Witwatersrand, Johannesburg

    J. C. Allan

Authors
  1. J. Gillman
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  2. Christine Gilbert
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  3. E. Epstein
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  4. J. C. Allan
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Gillman, J., Gilbert, C., Epstein, E. et al. Uncoupling of the disorder of carbohydrate metabolism from fat metabolism in experimentally-produced diabetes in baboons(Papio ursinus). Experientia 14, 79–80 (1958). https://doi.org/10.1007/BF02159019

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  • DOI: https://doi.org/10.1007/BF02159019

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