Summary
A study was made of the influence of local (liver field) and total irradiation (1,000 rl) on the enzymatic activity of isolated liver mitochondria from adult rats. While the succinodehydrogenase activity remains unaltered, the oxydation of pyruvate — as well as the structural stability of the mitochondria — are found to be reduced, entailing a decrease in the oxydative phosphorylation. These variations remain the same even after total or local irradiation.
References
R. L. Potter undF. H. Bethell, Federation Proc.11, 270 (1952).
E. Maxwell undG. Ashwell, Arch. Biochem.43, 389 (1953).
D. W. van Bekkum, H. J. Jongepier, H. T. M. Nieuwerkerk undJ. A. Cohen, Transactions Faraday Soc.49, 363 (1953), Brit. J. Radiol.27, 127 (1954),
W. C. Schneider undV. R. Potter, J. Biol. Chem.149, 217 (1943).
J. Raaflaub, Helv. physiol. Acta11, 142 (1953).
H. Aebi undI. Abelin, Biochem. Z.324, 364 (1953).
H. Aebi undI. Abelin, Biochem. Z.324, 364 (1953).
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Ryser, H., Aebi, H. & Zuppinger, A. Veränderungen in der Mitochondrienfraktion der Rattenleber nach Total- und Leberfeldbestrahlung (1000 r). Experientia 10, 304–305 (1954). https://doi.org/10.1007/BF02158741
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DOI: https://doi.org/10.1007/BF02158741