, Volume 10, Issue 7, pp 298–300 | Cite as

Zur Kenntnis des Muscarins

  • C. H. Eugster
  • P. G. Waser
Kurze Mitteilungen


The alkaloid muscarin was isolated from fly agaric. The analyses of crystallized salts (chloride, tetra-chloroaurate,Reinecke's salt) led to C9H20O2N+ as the simplest formula. The presence of aldehyde and tri-methyl-ammonium groups, which had been assumed hitherto, could not be proved. The quaternary nature of the nitrogen atom was shown. Pharmacological tests on frog heart, rabbit gut and cats show the purely peripheral parasympathomimetic effect of the smallest doses.


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Copyright information

© Birkhäuser Verlag 1954

Authors and Affiliations

  • C. H. Eugster
    • 1
  • P. G. Waser
    • 1
  1. 1.Chemisches Institut und Pharmakologisches Institut der Universität ZürichSwitzerland

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