Summary
Quinic acid methyl ester, having the 1.4 and 5 hydroxy-groups suitably blocked, was condensed with the carbonilcaffeic acid chloride.
Gradual hydrolysis of the condensation compound gave place to chlorogenic acid.
References
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Panizzi, L., Scarpati, M.L. & Oriente, G. Sintesi dell'acido clorogenico. Experientia 11, 383–384 (1955). https://doi.org/10.1007/BF02158491
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DOI: https://doi.org/10.1007/BF02158491