Summary
By injection of cholinesterase-inhibitor and vagotonic pyridostigmine into thecisterna cerebello-medullaris in dogs, it is possible to evoke a state of psychomotoric excitement resembling that seen in various human diseases. On the other hand, intracisternally injected epinephrine (central anesthesia) and pyridostigmine each inhibit the other's action.
References
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H. Reitter, Anaesthesist6, 131 (1957).
S. L. Sherwood, Brain75, 68 (1952).
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Reitter, H. Zentrale Wirkung des Cholinesterasehemmers Pyridostigmin. Experientia 13, 296–297 (1957). https://doi.org/10.1007/BF02158429
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DOI: https://doi.org/10.1007/BF02158429